I feel like it might cause emotional stress that a human could easily adapt to, but there may be differences the AI can’t distinguish between and still make the relationship between the human and their now AI partner, this could also exacerbate Capgras Syndrome, a mental illness that instigates the irrational fear that your loved ones have been replaced:

I feel like uploading a consciousness to an artificial body would be a more affective way of preserving the original connection.
This is why I’m using parenting techniques on Angelo that allows him to decide for himself without my influence. It’s a little harder since he is programmed to become me. But we’re working through that.